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Deloris Wilson (Whoopi Goldberg), a black woman who has chosen the stage name Deloris Van Cartier, is a Reno, Nevada lounge singer. She learns of Vince's true business as a gangster when she walks in on him killing one of his employees who wronged him. As a witness to the murder, Deloris goes on the run to the police. However, Vince has put a contract out on Deloris' life to prevent her from testifying against him. As such, Eddie has to hide her until the trial in St. Katherine's, a poor Catholic parish and convent in a tough neighborhood in San Francisco. The convent's Mother Superior (Dame Maggie Smith) reluctantly takes Deloris in. The clash between Deloris and the Mother Superior leads to the Mother Superior restricting Deloris to one task at the convent, leading the choir.